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(R)-3-Nitrobiphenyline: Wikis

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(R)-3-Nitrobiphenyline
Systematic (IUPAC) name
(R)-2-[1-(3'-Nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole
Identifiers
CAS number  ?
ATC code  ?
PubChem 16757089
Chemical data
Formula C 17H17N3O3  
Mol. mass 311.334 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

(R)-3-Nitrobiphenyline is a drug which acts as an α2-adrenergic agonist, selective for the α2C subtype, as well as being a weak antagonist at the α2A and α2B subtypes.[1]

References

  1. ^ Crassous PA, Cardinaletti C, Carrieri A, Bruni B, Di Vaira M, Gentili F, Ghelfi F, Giannella M, Paris H, Piergentili A, Quaglia W, Schaak S, Vesprini C, Pigini M (August 2007). "Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist". Journal of Medicinal Chemistry 50 (16): 3964–8. doi:10.1021/jm061487a. PMID 17630725.  
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