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25I-NBMD: Wikis

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25I-NBMD
Systematic (IUPAC) name
2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2,3-methylenedioxyphenyl)methyl]ethanamine
Identifiers
CAS number  ?
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Chemical data
Formula C 18H20INO4  
Mol. mass 441.259 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
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Half life  ?
Excretion  ?
Therapeutic considerations
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25I-NBMD (NBMD-2C-I) is a derivative of the phenethylamine hallucinogen 2C-I, discovered in 2006 by a team at Purdue University led by David Nichols. It acts as a potent agonist for the 5HT2A receptor with a Ki of 0.049nM at the human 5HT2A receptor.[1][2]

See also

References

  1. ^ Braden MR, Parrish JC, Naylor JC, Nichols DE. Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists. Molecular Pharmacology. 2006 Dec;70(6):1956-64. PMID 17000863
  2. ^ Michael Robert Braden PhD. Towards a biophysical understanding of hallucinogen action. Purdue University 2007.
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