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More info on 3-(p-Fluorobenzoyloxy)tropane

3-(p-Fluorobenzoyloxy)tropane: Wikis


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Systematic (IUPAC) name
CAS number 172883-97-5
ATC code  ?
PubChem 5147770
Chemical data
Formula C 15H18FNO2  
Mol. mass 263.307
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a stimulant and local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic. It has been investigated as a potential radiolabelled agent for studying receptor binding,[1] but was not adopted for this application. It was first reported as a designer drug analogue of cocaine by the European Monitoring Centre for Drugs and Drug Addiction in 2008.[2]

The ortho-hydroxy benzoyl ester is a strong DRI substitution arrangement (Satendra Singh, 2000) (p 970-973).


  1. ^ Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN 0306440350
  2. ^ [1]

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