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3-Fluoroamphetamine: Wikis

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3-Fluoroamphetamine
Systematic (IUPAC) name
1-(3-fluorophenyl)propan-2-amine
Identifiers
CAS number 1626-71-7
ATC code  ?
PubChem 121501
Chemical data
Formula C 9H12FN 
Mol. mass 153.196
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and noradrenaline release over serotonin.[1] It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.[2]

See also

References

  1. ^ Negus SS, Mello NK, Blough BE, Baumann MH, Rothman RB. Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics. 2007 Feb;320(2):627-36. PMID 17071819
  2. ^ Wee S, Anderson KG, Baumann MH, Rothman RB, Blough BE, Woolverton WL. Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs. Journal of Pharmacology and Experimental Therapeutics. 2005 May;313(2):848-54. PMID 15677348
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