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4'-Methyl-α-pyrrolidinopropiophenone: Wikis

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4'-Methyl-α-pyrrolidinopropiophenone
Systematic (IUPAC) name
1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-propanone
Identifiers
CAS number  ?
ATC code  ?
PubChem 6430745
Chemical data
Formula C 14H19NO 
Mol. mass 217.306 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
The stimulant drug should not be confused with the opioid drug MPPP

4'-Methyl-α-pyrrolidinopropiophenone (MPPP) is a stimulant drug. It is very structurally similar to α-PPP, with only one added methyl group in the para position on the phenyl ring. MPPP was sold in Germany as a designer drug in the late 1990s and early 2000s,[1][2][3] along with a number of other pyrrolidinophenone derivatives,[4][5] although it has never achieved the same international popularity as its better-known relations α-PPP and MDPV.

See also

References

  1. ^ Springer D, Peters FT, Fritschi G, Maurer HH. Studies on the metabolism and toxicological detection of the new designer drug 4'-methyl-alpha-pyrrolidinopropiophenone in urine using gas chromatography-mass spectrometry. Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences. 2002 Jun 15;773(1):25-33. PMID 12015267
  2. ^ Springer D, Paul LD, Staack RF, Kraemer T, Maurer HH. Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes. Drug Metabolism and Disposition. 2003 Aug;31(8):979-82. PMID 12867484
  3. ^ Springer D, Fritschi G, Maurer HH. Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4'-methyl-alpha-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry. Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences. 2003 Nov 5;796(2):253-66. PMID 14581066
  4. ^ Maurer HH, Kraemer T, Springer D, Staack RF. Chemistry, pharmacology, toxicology, and hepatic metabolism of designer drugs of the amphetamine (ecstasy), piperazine, and pyrrolidinophenone types: a synopsis. Therapeutic Drug Monitoring. 2004 Apr;26(2):127-31. PMID 15228152
  5. ^ Staack RF, Maurer HH. Metabolism of designer drugs of abuse. Current Drug Metabolism. 2005 Jun;6(3):259-74. PMID 15975043
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