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4-Benzylpiperidine: Wikis


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Systematic (IUPAC) name
CAS number 31252-42-3
ATC code  ?
PubChem 31738
Chemical data
Formula C12H17N 
Mol. mass 175.270 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

4-Benzylpiperidine is a drug and research chemical used in scientific studies. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin.[1] It has a fast onset of action and a short duration.[1] It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.[2]

See also


  1. ^ a b Negus SS, Baumann MH, Rothman RB, Mello NK, Blough BE. (2009). "Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.". J Pharmacol Exp Ther. 329 (1): 272–281. PMID 19151247. 
  2. ^ Arai Y, Hamamichi N, Kinemuchi H. (1986). "Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.". Neurosci Lett. 70 (2): 255–260. PMID 3490636. 


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