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More info on 5,7-Dichlorokynurenic acid

5,7-Dichlorokynurenic acid: Wikis

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DCKA
DCKA.svg
IUPAC name
Identifiers
CAS number 131123-76-7
PubChem 1779
SMILES
Properties
Molecular formula C10H5Cl2NO3
Molar mass 258.058 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

DCKA (5,7-dichlorokynurenic acid) is a selective NMDA receptor (NMDAR) antagonist acting at the glycine site on the NMDAR complex.[1]

References

  1. ^ McNamara D, Smith EC, Calligaro DO, O'Malley PJ, McQuaid LA, Dingledine R. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neuroscience Letters. 1990 Nov 27;120(1):17-20. PMID 2149877
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