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More info on 5,7-Dihydroxytryptamine

5,7-Dihydroxytryptamine: Wikis

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5,7-Dihydroxytryptamine
5,7-Dihydroxytryptamine.png
IUPAC name
Other names 5,7-Dihydroxytryptamine
Identifiers
CAS number 31363-74-3
PubChem 35781
SMILES
InChI
InChI key LXWHQTNFZDTKBH-UHFFFAOYAC
ChemSpider ID 32913
Properties
Molecular formula C10H12N2O2
Molar mass 192.214
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

5,7-Dihydroxytryptamine (5,7-DHT) is a neurotoxin used to selectively kill serotonergic neurons in scientific research, in the same way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic cells.[1][2]

See also

References

  1. ^ Cairncross KD, Cox B, Forster C, Wren A. The ability of local injection of 6-OHDA, 5,6-DHT and 5,7-DHT into the olfactory bulbs to mimic the effects of bilateral bulbectomy in the rat. British Journal of Pharmacology. 1977 Sep;61(1):145P-146P. PMID 912193
  2. ^ Liu J, Chu YX, Zhang QJ, Wang S, Feng J, Li Q. 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus alters neuronal activity of the subthalamic nucleus in normal and 6-hydroxydopamine-lesioned rats. Brain Research. 2007 May 29;1149:216-22. PMID 17376410
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