The Full Wiki

More info on 5-Fluoro-DMT

5-Fluoro-DMT: Wikis

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
CAS number 22120-36-1
ATC code  ?
PubChem 2762738
Chemical data
Formula C 12H15FN2  
Mol. mass 206.259 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

5-Fluoro-N,N-dimethyltryptamine (5-F-DMT) is a tryptamine derivative related to compounds such as 5-Bromo-DMT and 5-Methoxy-DMT. Fluorination of hallucinogenic tryptamines either reduces or has little effect on 5-HT2A/C receptor affinity or efficacy, although 6-fluoro-DET is inactive as a hallucinogen despite acting as a 5-HT2A agonist (cf. lisuride), while 4-fluoro-5-methoxy-DMT is a much stronger agonist at 5-HT1A than 5-HT2A.[1][2]

See also


  1. ^ Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE. Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines. Journal of Medicinal Chemistry. 2000 Nov 30;43(24):4701-10. PMID 11101361
  2. ^ Rabin RA, Regina M, Doat M, Winter JC. 5-HT2A receptor-stimulated phosphoinositide hydrolysis in the stimulus effects of hallucinogens. Pharmacology, Biochemistry and Behaviour. 2002 May;72(1-2):29-37. PMID 11900766

Got something to say? Make a comment.
Your name
Your email address