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8-OH-PBZI: Wikis

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8-OH-PBZI
Systematic (IUPAC) name
(3aS,9bR)-3-propyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-8-ol
Identifiers
ATC code none
PubChem 10353845
Chemical data
Formula C15H21NO 
Mol. mass 231.333 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

8-OH-PBZI is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D3 receptor.[1][2][3]

References

  1. ^ Scheideler MA, Martin J, Hohlweg R, Rasmussen JS, Naerum L, Ludvigsen TS, Larsen PJ, Korsgaard N, Crider AM, Ghosh D, Cruse SF, Fink-Jensen A. The preferential dopamine D3 receptor agonist cis-8-OH-PBZI induces limbic Fos expression in rat brain. European Journal of Pharmacology. 1997 Nov 27;339(2-3):261-70. PMID 9473144
  2. ^ Fink-Jensen A, Nielsen EB, Hansen L, Scheideler MA. Behavioral and neurochemical effects of the preferential dopamine D3 receptor agonist cis-8-OH-PBZI. European Journal of Pharmacology. 1998 Jan 26;342(2-3):153-61. PMID 9548380
  3. ^ Malik P, Andersen MB, Peacock L. The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia. Pharmacology, Biochemistry and Behavior. 2004 Aug;78(4):805-10. PMID 15301939
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