90Y-DOTA-biotin: Wikis

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Categories: Radiopharmaceuticals > Biomolecules

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⁹⁰Y-DOTA-biotin is a radioactive substance (yttrium-90) joined by a chemical link (DOTA) to biotin, a vitamin. It is often used in pretargeted radioimmunotherapy, especially in cancer research.

References

Domingo RJ, Reilly RM (2000). "Pre-targeted radioimmunotherapy of human colon cancer xenografts in athymic mice using streptavidin-CC49 monoclonal antibody and 90Y-DOTA-biotin". Nuclear medicine communications 21 (1): 89–96. doi:10.1097/00006231-200001000-00015. PMID 10717908.

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Wiktionary

Up to date as of January 14, 2010

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English

Noun

Singular
90Y-DOTA-biotin

Plural
uncountable

90Y-DOTA-biotin (uncountable)

(oncology) The vitamin biotin labelled with radioactive (yttrium-90); it is used in the treatment of cancer where it seeks out tumor cells that have been targeted by an antibody linked to strepavidin and kill them.

Categories: English nouns | Oncology

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