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ATP-binding cassette, sub-family F (GCN20), member 2
Symbols ABCF2; ABC28; DKFZp586K1823; EST133090; HUSSY-18; M-ABC1
External IDs MGI1351657 HomoloGene21408 GeneCards: ABCF2 Gene
RNA expression pattern
PBB GE ABCF2 207622 s at tn.png
PBB GE ABCF2 207623 at tn.png
PBB GE ABCF2 209247 s at tn.png
More reference expression data
Species Human Mouse
Entrez 10061 27407
Ensembl ENSG00000033050 ENSMUSG00000028953
UniProt Q9UG63 Q3UVI9
RefSeq (mRNA) NM_005692 NM_013853
RefSeq (protein) NP_005683 NP_038881
Location (UCSC) Chr 7:
150.54 - 150.56 Mb
Chr 5:
24.08 - 24.09 Mb
PubMed search [1] [2]

ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.[1][2]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.[2]


See also


  1. ^ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database". Hum Mol Genet 5 (10): 1649-55. PMID 8894702.  
  2. ^ a b "Entrez Gene: ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2".  

Further reading

  • Klein I, Sarkadi B, Váradi A (2000). "An inventory of the human ABC proteins.". Biochim. Biophys. Acta 1461 (2): 237–62. PMID 10581359.  
  • Dean M, Rzhetsky A, Allikmets R (2001). "The human ATP-binding cassette (ABC) transporter superfamily.". Genome Res. 11 (7): 1156–66. doi:10.1101/gr.184901. PMID 11435397.  
  • Hogue DL, Liu L, Ling V (1999). "Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.". J. Mol. Biol. 285 (1): 379–89. doi:10.1006/jmbi.1998.2259. PMID 9878413.  
  • Zhang F, Hogue DL, Liu L, et al. (2000). "M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein.". FEBS Lett. 478 (1-2): 89–94. doi:10.1016/S0014-5793(00)01823-8. PMID 10922475.  
  • Ye Z, Connor JR (2000). "cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.". Biochem. Biophys. Res. Commun. 275 (1): 223–7. doi:10.1006/bbrc.2000.3282. PMID 10944468.  
  • Stanchi F, Bertocco E, Toppo S, et al. (2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences.". Yeast 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.  
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Tsuda H, Ito YM, Ohashi Y, et al. (2006). "Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses.". Clin. Cancer Res. 11 (19 Pt 1): 6880–8. doi:10.1158/1078-0432.CCR-05-0751. PMID 16203778.  
  • Nishimura S, Tsuda H, Ito K, et al. (2007). "Differential expression of ABCF2 protein among different histologic types of epithelial ovarian cancer and in clear cell adenocarcinomas of different organs.". Hum. Pathol. 38 (1): 134–9. doi:10.1016/j.humpath.2006.06.026. PMID 16996567.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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