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AL-38022A: Wikis

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AL-38022A
Systematic (IUPAC) name
(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine
Identifiers
CAS number  ?
ATC code  ?
PubChem 22496603
Chemical data
Formula C 13H17N3O 
Mol. mass 231.293 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 106–107 °C (223–225 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications. It acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around 4x less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests on animals, it fully substituted for both DOM and 5-MeO-DMT.[1]

See also

References

  1. ^ May JA, Sharif NA, Chen HH, Liao JC, Kelly CR, Glennon RA, Young R, Li JX, Rice KC, France CP. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT(2) receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, Biochemistry and Behaviour. 2009 Jan;91(3):307-14. PMID 18718483
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