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Updated live from Wikipedia, last check: May 24, 2013 08:21 UTC (44 seconds ago)

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AT rich interactive domain 2 (ARID, RFX-like)
Identifiers
Symbols ARID2; p200; BAF200; DKFZp686G052; DKFZp779P0222; FLJ30619; KIAA1557
External IDs OMIM609539 MGI1924294 HomoloGene14601 GeneCards: ARID2 Gene
RNA expression pattern
PBB GE ARID2 gnf1h01782 at tn.png
PBB GE ARID2 gnf1h01783 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 196528 77044
Ensembl ENSG00000189079 ENSMUSG00000033237
UniProt Q68CP9 n/a
RefSeq (mRNA) NM_152641 NM_175251
RefSeq (protein) NP_689854 NP_780460
Location (UCSC) Chr 12:
44.41 - 44.59 Mb
Chr 15:
96.12 - 96.23 Mb
PubMed search [1] [2]

AT-rich interactive domain-containing protein 2 is a protein that in humans is encoded by the ARID2 gene.[1]

ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005).[supplied by OMIM][1]

References

Further reading

  • Martens JA, Winston F (2003). "Recent advances in understanding chromatin remodeling by Swi/Snf complexes.". Curr. Opin. Genet. Dev. 13 (2): 136–42. doi:10.1016/S0959-437X(03)00022-4. PMID 12672490.  
  • Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (4): 273–81. PMID 10997877.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Mohrmann L, Langenberg K, Krijgsveld J, et al. (2004). "Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes.". Mol. Cell. Biol. 24 (8): 3077–88. doi:10.1128/MCB.24.8.3077-3088.2004. PMID 15060132.  
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.  
  • Diederichs S, Bäumer N, Ji P, et al. (2004). "Identification of interaction partners and substrates of the cyclin A1-CDK2 complex.". J. Biol. Chem. 279 (32): 33727–41. doi:10.1074/jbc.M401708200. PMID 15159402.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Patsialou A, Wilsker D, Moran E (2005). "DNA-binding properties of ARID family proteins.". Nucleic Acids Res. 33 (1): 66–80. doi:10.1093/nar/gki145. PMID 15640446.  
  • Wilsker D, Probst L, Wain HM, et al. (2005). "Nomenclature of the ARID family of DNA-binding proteins.". Genomics 86 (2): 242–51. doi:10.1016/j.ygeno.2005.03.013. PMID 15922553.  
  • Yan Z, Cui K, Murray DM, et al. (2005). "PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.". Genes Dev. 19 (14): 1662–7. doi:10.1101/gad.1323805. PMID 15985610.  
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.  
  • Zhang X, Azhar G, Zhong Y, Wei JY (2006). "Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation.". Biochem. Biophys. Res. Commun. 346 (3): 794–801. doi:10.1016/j.bbrc.2006.05.211. PMID 16782067.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.








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