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AT rich interactive domain 3B (BRIGHT-like)
Identifiers
Symbols ARID3B; BDP; DRIL2
External IDs MGI1930768 HomoloGene4721 GeneCards: ARID3B Gene
RNA expression pattern
PBB GE ARID3B 218964 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10620 56380
Ensembl ENSG00000179361 ENSMUSG00000004661
UniProt n/a n/a
RefSeq (mRNA) NM_006465 NM_019689
RefSeq (protein) NP_006456 NP_062663
Location (UCSC) Chr 15:
72.62 - 72.68 Mb
Chr 9:
57.59 - 57.63 Mb
PubMed search [1] [2]

AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene.[1]

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.[1]

References

Further reading

  • Kortschak RD, Tucker PW, Saint R (2000). "ARID proteins come in from the desert.". Trends Biochem. Sci. 25 (6): 294–9. doi:10.1016/S0968-0004(00)01597-8. PMID 10838570.  
  • Numata S, Claudio PP, Dean C, et al. (1999). "Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product.". Cancer Res. 59 (15): 3741–7. PMID 10446990.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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