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ATF7: Wikis


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Activating transcription factor 7
Symbols ATF7; ATFA; MGC57182
External IDs OMIM606371 MGI2443472 HomoloGene4994 GeneCards: ATF7 Gene
RNA expression pattern
PBB GE ATF7 206684 s at tn.png
More reference expression data
Species Human Mouse
Entrez 11016 223922
Ensembl ENSG00000170653 ENSMUSG00000052414
UniProt P17544 Q3TZR9
RefSeq (mRNA) NM_006856 NM_146065
RefSeq (protein) NP_006847 NP_666177
Location (UCSC) Chr 12:
52.2 - 52.31 Mb
Chr 15:
102.36 - 102.39 Mb
PubMed search [1] [2]

Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene.[1][2][3]



ATF7 has been shown to interact with PTP4A1.[2]


  1. ^ Gaire M, Chatton B, Kedinger C (Aug 1990). "Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells". Nucleic Acids Res 18 (12): 3467–73. PMID 1694576.  
  2. ^ a b Peters CS, Liang X, Li S, Kannan S, Peng Y, Taub R, Diamond RH (Apr 2001). "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase". J Biol Chem 276 (17): 13718–26. doi:10.1074/jbc.M011562200. PMID 11278933.  
  3. ^ "Entrez Gene: ATF7 activating transcription factor 7".  

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.  
  • Hamard PJ, Dalbies-Tran R, Hauss C, et al. (2005). "A functional interaction between ATF7 and TAF12 that is modulated by TAF4.". Oncogene 24 (21): 3472–83. doi:10.1038/sj.onc.1208565. PMID 15735663.  
  • Werner SR, Lee PA, DeCamp MW, et al. (2004). "Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases.". Cancer Lett. 202 (2): 201–11. doi:10.1016/S0304-3835(03)00517-2. PMID 14643450.  
  • Newman JR, Keating AE (2003). "Comprehensive identification of human bZIP interactions with coiled-coil arrays.". Science 300 (5628): 2097–101. doi:10.1126/science.1084648. PMID 12805554.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Newman SP, Bates NP, Vernimmen D, et al. (2000). "Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer.". Oncogene 19 (4): 490–7. doi:10.1038/sj.onc.1203416. PMID 10698518.  
  • Goetz J, Chatton B, Mattei MG, Kedinger C (1997). "Structure and expression of the ATFa gene.". J. Biol. Chem. 271 (47): 29589–98. doi:10.1074/jbc.271.47.29589. PMID 8939888.  
  • Bocco JL, Bahr A, Goetz J, et al. (1996). "In vivo association of ATFa with JNK/SAP kinase activities.". Oncogene 12 (9): 1971–80. PMID 8649858.  
  • Pescini R, Kaszubska W, Whelan J, et al. (1994). "ATF-a0, a novel variant of the ATF/CREB transcription factor family, forms a dominant transcription inhibitor in ATF-a heterodimers.". J. Biol. Chem. 269 (2): 1159–65. PMID 8288576.  
  • Zhou Q, Gedrich RW, Engel DA (1995). "Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB.". J. Virol. 69 (7): 4323–30. PMID 7769693.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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