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Acetohydroxamic acid: Wikis


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Acetohydroxamic acid
Systematic (IUPAC) name
ethanehydroxamic acid
Identifiers
CAS number 546-88-3
ATC code G04BX03
PubChem 1990
DrugBank APRD00774
ChemSpider 1913
Chemical data
Formula C 2H5NO2  
Mol. mass 75.0666 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
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Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965).

References

  • W. Fishbein and P. Carbone J Biol Chem. 1965 Jun;240:2407-14







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