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Acrivastine: Wikis


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Systematic (IUPAC) name
prop-1-enyl]pyridin-2-yl}prop-2-enoic acid
CAS number 87848-99-5
ATC code R06AX18
PubChem 5284514
ChemSpider 4447574
Chemical data
Formula C 22H24N2O2  
Mol. mass 348.438 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 1.5 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. B(US)
Legal status -only (US)
Routes oral

Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.

It is sold under the brand name Benadryl Allergy Relief in the U.K. by Pfizer, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by Pfizer in the U.K. This drug is currently not available as a generic in the U.K.[1]

In the U.S., acrivastine is the active ingredient in the Semprex brand. Semprex-D is also acrivastine based, but contains a decongestant, pseudoephedrine. Semprex-D is marketed in the U.S. by UCB, Inc..[2][3]


  1. ^ Cheapest hayfever remedies 2007, Money Saving expert, May 15,2007
  2. ^ [ Products - United States] UCB
  3. ^ [ SEMPREX-D - acrivastine and pseudoephedrine hydrochloride capsule] U.S. National Library of Medicine, National Institutes of Health, Health & Human Services, May 2008


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