The Full Wiki

More info on Activating protein 2

Activating protein 2: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Symbol TFAP2A
Alt. symbols TFAP2, AP2TF
Entrez 7020
HUGO 11742
OMIM 107580
RefSeq NM_003220
UniProt P05549
Other data
Locus Chr. 6 p22.3
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Symbol TFAP2B
Alt. symbols AP2-B
Entrez 7021
HUGO 11743
OMIM 601601
RefSeq NM_003221
UniProt Q92481
Other data
Locus Chr. 6 p12
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Symbol TFAP2C
Entrez 7022
HUGO 11744
OMIM 601602
RefSeq NM_003222
UniProt Q92754
Other data
Locus Chr. 20 q13.2
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
Symbol TFAP2D
Alt. symbols TFAP2BL1
Entrez 83741
HUGO 15581
OMIM 610161
RefSeq NM_172238
UniProt Q7Z6R9
Other data
Locus Chr. 6 p12.3
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
Symbol TFAP2E
Alt. symbols AP2E
Entrez 339488
HUGO 30774
RefSeq NM_178548
UniProt Q6VUC0
Other data
Locus Chr. 1 p34.3

Activating Protein 2 (AP-2) is a family of closely related transcription factors[1][2] which plays a critical role in regulating gene expression during early development.[3]


  1. ^ Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science 251 (4997): 1067–71. doi:10.1126/science.1998122. PMID 1998122.  
  2. ^ Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi:10.1101/gad.5.4.670. PMID 2010091.  
  3. ^ Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene 260 (1-2): 1–12. doi:10.1016/S0378-1119(00)00454-6. PMID 11137286.  

External links



Got something to say? Make a comment.
Your name
Your email address