| Acquired immunodeficiency syndrome (AIDS) | |
|---|---|
| Classification and external resources | |
![]() The Red ribbon is a symbol for solidarity with HIV-positive people and those living with AIDS. |
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| ICD-10 | B24. |
| ICD-9 | 042 |
| DiseasesDB | 5938 |
| MedlinePlus | 000594 |
| eMedicine | emerg/253 |
| MeSH | D000163 |
| List of abbreviations used in this article AIDS: Acquired immune deficiency syndrome
HIV: Human immunodeficiency virus CD4+: CD4+ T helper cells CCR5: Chemokine (C-C motif) receptor 5 CDC: Centers for Disease Control and Prevention WHO: World Health Organization PCP: Pneumocystis pneumonia TB: Tuberculosis MTCT: Mother-to-child transmission HAART: Highly active antiretroviral therapy STI/STD: Sexually transmitted infection/disease |
Contents |
| Exposure Route | Estimated infections per 10,000 exposures to an infected source |
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|---|---|---|---|---|
| Blood Transfusion | 9,000[80] | |||
| Childbirth (to child) | 2,500[61] | |||
| Needle-sharing injection drug use | 67[81] | |||
| Percutaneous needle stick | 30[82] | |||
| Receptive anal intercourse* | 50[83][84] | |||
| Insertive anal intercourse* | 6.5[83][84] | |||
| Receptive penile-vaginal intercourse* | 10[83][84][85] | |||
| Insertive penile-vaginal intercourse* | 5[83][84] | |||
| Receptive oral intercourse*§ | 1[84] | |||
| Insertive oral intercourse*§ | 0.5[84] | |||
| * assuming no condom use § source refers to oral intercourse performed on a man |
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Aids
Acquired Immunodeficiency Syndrome or Acquired Immune Deficiency Syndrome (AIDS) is a syndrome caused by a virus called HIV.
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About 3,000,000 people died because of AIDS in 2004. About 500,000 of these people were children. About 40,000,000 people in the world had HIV in 2004.
Most of the people who have HIV live in Africa. Most of the children who die from AIDS live in Africa.
Many people with HIV do not know they have it. The number of people with HIV is unknown.
Scientists believe the first person who got HIV was a person in Africa. This happened when Simian Immunodeficiency Virus (SIV) went from chimpanzees to humans
HIV attacks the immune system. This is how the body fights infections. This is also how the body helps stop cancers. So people with HIV are more likely to have infections and cancers. They may even die of minor illnesses like the common cold, which normally healthy people can recover from.
Not every person who has HIV has AIDS. When people first get HIV they are not very sick. They can be healthy for years. When they get sick from HIV it is called AIDS.
If someone has HIV they are called HIV positive.
Someone has AIDS if they have HIV and either:
Some of the infections and cancers that people with AIDS get, most healthy people do not get. People who have good immune systems do not get these diseases. Many of these diseases are called AIDS defining illnesses. Some AIDS defining illnesses are:
The blood test that defines AIDS is the CD4 T-cell count. T-cells are white blood cells. These are cells that fight infection. HIV goes into T-cells and kills them. When HIV infection gets very bad the number of CD4 T-cells in the blood goes down. CD4 is a protein outside of the T-cell. Some T-cells have this protein. They are called CD4 positive T-cells, CD4 T-cells or sometimes T4 cells.
When someone has HIV and their CD4 T-cell count (number of cells in the blood) is below 200 cells/microliter it means they have AIDS.
There are medicines that help people with AIDS. These are called antiretroviral medicines (or antiretrovirals.) Anti- means against. HIV is a retrovirus. So antiretroviral means fights retroviruses.
Antiretrovirals cannot cure AIDS. This means they cannot make all of the virus leave a person's body. But they can make people with AIDS more healthy. Antiretrovirals help people fight the HIV virus. This makes their immune systems work better. So antiretrovirals are a treatment but not a cure for HIV.
People with HIV/AIDS who take antiretroviral medicines live longer. They live longer without getting AIDS defining illnesses. But after a long time, the HIV virus learns how to fight the antiretrovirals. The HIV virus is not killed by this medicine. HIV becomes resistant to the medicine. Then the resistant HIV hurts the immune system and the person may get AIDS.
Sometimes when HIV is resistant to one medicine, another medicine can be used. To make less resistance happen, people with AIDS take more than one medicine at the same time. They may take 2-4 medicines at once. This is sometimes called a cocktail or AIDS cocktail.
When HIV gets resistant to one medicine, this is changed to another medicine. So the AIDS cocktail that people with AIDS take changes over time. But after a long time, the HIV learns to be resistant to many drugs. This is called multi-drug-resistant (acronym MDR) HIV. After the HIV in a person has MDR-HIV there may be no more medicines to treat them. So scientists keep trying to find new medicines to fight HIV. The five most important HIV medicines are:
Many people who die of AIDS, especially in Africa, leave behind children who are still alive, and who may need help being taken care of. These children are called AIDS orphans.
There are many ways people fight the AIDS epidemic.
The most important way to stop HIV/AIDS is education. People can get HIV from sex and from blood. Children can also get HIV from their mothers (when they grow inside pregnant mothers and when they drink breast milk.) Sex is one way to get HIV. If people use condoms when they have sex, there is a much smaller chance of catching HIV.
A person can also get HIV by sharing needles. This means using a needle that has not been cleaned after someone else has used it. Some people who take illegal drugs like heroin and cocaine take these drugs by needle. Some of these people share needles. If one person has HIV and he shares his needles, he can give HIV to other people. But if people have clean needles or if they know how to clean needles, they do not get HIV as much.
Many people do not know that condoms and clean needles help stop HIV. They may not even know that sharing needles and sex with someone who has HIV can make them get HIV. Even if people know about condoms and clean needles, they may not have condoms and clean needles.
There are some people who do not want people to know about condoms or clean needles, or do not want people to have condoms or clean needles. They believe that if people know about condoms and have condoms they will have more sex. They believe that if people have clean needles they will use illegal drugs more. Many of these people think this because of their religion. For example, the Catholic church does not want people to have or use condoms.[1] They do not want people to have condoms because they do not think people should have sex unless they are married. They also think that married people should not use condoms, because they believe that if people have sex, it should only be to make a baby.
Scientists who study (look at and learn about) people who use condoms, see that if teenagers (children 13-19) learn about condoms (and other birth control) they have less unsafe sex. Scientists see that learning about these things does not make teenagers start having sex earlier. The teenagers also have safer sex. Safer sex means doing things (like wearing condoms) to try not to get pregnant or get sexually transmitted diseases (STDs or STIs) like HIV, gonorrhea, and syphilis. Using a condom works very well for keeping people from getting pregnant or getting STDs if people know how to use a condom the right way.[1] [2]
Scientists have also learned that if a city has a needle exchange program it will have fewer people who use illegal drugs. Needle exchange programs are where people can come in and trade dirty needles for clean needles. This means that if they use drugs they will be more safe. But needle exchange programs do more than give people clean needles. They teach people about drugs. If people want to stop using drugs, they help them. [3]
The best way to stop HIV is a vaccine. There is no vaccine for HIV yet. Many scientists are looking for an HIV vaccine. Even one that protected some people from HIV would save millions of people's lives.
Some scientists think that HIV is not the cause of AIDS. They think AIDS is the result of illegal drug use, drugs used to treat HIV infection, malnutrition, poverty, multiple infections, and other assaults on the immune system. Most scientists disagree with this viewpoint and feel the evidence for HIV as the cause of AIDS is overwhelming. See the other websites below.
These sites may not be simple.
These may be unsimple.
rue:АІДС
Here are sentences from other pages on AIDS, which are similar to those in the above article.
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