The Full Wiki

More info on Alimemazine

Alimemazine: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
CAS number 84-96-8
ATC code D04AA10 R06AD02, R06AD05
PubChem 5574
DrugBank APRD00258
ChemSpider 5373
Chemical data
Formula C 18H22N2S 
Mol. mass 298.447 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 5 hrs
Excretion  ?
Therapeutic considerations
Pregnancy cat. C(AU)
Legal status
Routes Oral
 Yes check.svgY(what is this?)  (verify)

Alimemazine (INN), also known as trimeprazine (former BAN and USAN; trade names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, or Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine).[1] It also acts as a sedative and anti-emetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine (Thorazine), it is not used as an anti-psychotic treatment.[2] It is no longer available in the United States.[3] The elimination half life is approximately 5 hours.[4]


  1. ^ "PubChem CID 78032".  
  2. ^ "Drugbank:Trimeprazine".  
  3. ^ "MedlinePlus:Trimeprazine".  
  4. ^ Hu OY; Gfeller E, Perrin JH, Curry SH (March 1986). "Relative bioavailability of trimeprazine tablets investigated in man using HPLC with electrochemical detection". J Pharm Pharmacol 38 (3): 172–6. PMID 2871150.  


Got something to say? Make a comment.
Your name
Your email address