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Alizapride
Systematic (IUPAC) name
N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-1 H-benzo[d][1,2,3]triazole-5-carboxamide
Identifiers
CAS number 59338-93-1
ATC code A03FA05
PubChem 43008
ChemSpider 39202
Chemical data
Formula C 16H21N5O2  
Mol. mass 315.37 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral, intramuscular, intravenous
 Yes check.svgY(what is this?)  (verify)

Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide.[1]

Alizapride is marketed under various trade names including Litican, Plitican, Superan and Vergentan.[2]

References

  1. ^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20. PMID 3048762.  
  2. ^ (French) "Alizapride Chlorhydrate". BIAM. June 2, 1997. http://www.biam2.org/www/Sub4814.html. Retrieved 2007-08-14.  
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