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Alprenolol: Wikis

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Alprenolol
Systematic (IUPAC) name
(RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol
Identifiers
CAS number 13655-52-2
ATC code C07AA01
PubChem 2119
ChemSpider 2035
Chemical data
Formula C 15H23NO2  
Mol. mass 249.34 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Protein binding 80% - 90%
Metabolism  ?
Half life 2-3 hours → 4-OH-alprenolol
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral
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Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.[1] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.

References

  1. ^ Hickie JB (August 1970). "Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial". Med. J. Aust. 2 (6): 268–72. PMID 4393977.  
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