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Amodiaquine: Wikis


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Systematic (IUPAC) name
CAS number 86-42-0
ATC code P01BA06
PubChem 2165
DrugBank APRD00796
ChemSpider 2080
Chemical data
Formula C 20H22ClN3O 
Mol. mass 355.861 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 5.2 ± 1.7 (range 0.4 to 5.5) minutes
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
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Amodiaquine (trade names Camoquin, Flavoquine) is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.

Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like chloroquine, is generally well tolerated. Although licensed, this drug is not marketed in the United States but is widely available in Africa. Its use, therefore, is probably more practicable in long-term visitors and persons who will reside in Africa.[1]

Amodiaquine is a histamine N-methyltransferase inhibitor.




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