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Anterior chamber of eyeball
Schematic diagram of the human eye en.svg
Schematic diagram of the human eye.
Latin camera anterior bulbi oculi

The anterior chamber is the fluid-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium.[1] Aqueous humor is the fluid that fills the anterior chamber. Hyphema and glaucoma are two main pathologies in this area. In hyphema, blood fills the anterior chamber. In glaucoma, blockage of the canal of Schlemm prevents the normal outflow of aqueous humor, resulting in accumulation of fluid, increased intraocular pressure, and eventually blindness.

One peculiar feature of the anterior chamber is dampened immune response to allogenic grafts. This is called anterior chamber associated immune deviation (ACAID), a term introduced in 1981 by Streilein et al.[2]



See also


  1. ^ Cassin, B. and Solomon, S. (1990). Dictionary of eye terminology. Gainesville, Fla: Triad Pub. Co. ISBN 0-937404-33-0.  
  2. ^ Streilein JW, Niederkorn JY (May 1981). "Induction of anterior chamber-associated immune deviation requires an intact, functional spleen". J. Exp. Med. 153 (5): 1058–67. PMID 6788883.  

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