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Anthelmintic drugs: Wikis


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Anthelmintics or antihelminthics are drugs that expel parasitic worms (helminths) from the body, by either stunning or killing them. They may also be called vermifuges (stunning) or vermicides (killing).

Contents

Pharmaceutical classes

Examples of pharmaceuticals used as anthelmintics include:

Please note that many of these pharameuticals are extremely toxic. Taken in improper dosages they can be dangerous to humans as well as lethal to parasites.

Natural antihelmintics

Examples of naturally occurring anthelmintics include:

Please note that many natural vermifuges or anthelmintics are poisonous and, in improper dosages, dangerous to humans as well as parasites.

Anthelmintic resistance

The ability of worms to survive treatments that are generally effective at the recommended dose rate is considered a major threat to the future control of worm parasites of small ruminants and horses.

The clinical definition of resistance is a 95% or less reduction in a "Fecal Egg Count" test.

Treatment with an antihelminthic drug kills worms whose genotype renders them susceptible to the drug. Worms that are resistant survive and pass on their "resistance" genes. Resistant worms accumulate and finally treatment failure occurs. See drug resistance.

References

Footnotes

  1. ^ The Merck Index, 12th Ed., page 1119: entry 6611 Nicotine, Merck & Co. 1996
  2. ^ Arnold, M.D., Harry L. (1968). Poisonous Plants of Hawaii. Tokyo, Japan: Charles E. Tuttle Co.. pp. 51. ISBN 0804804745.  
  3. ^ "Peganum harmala". 2004. http://www.sdpi.org/alpine%20medicianl%20herbs/39.htm. Retrieved 2008-02-02.  

General references

  • Department of the Army Headquarters (2004). U.S. Army Survival Manual Fm 21-76. Barns & Noble Inc. ISBN 0-7607-4988-4.  

External links








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