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Aortoiliac occlusive disease: Wikis


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Aortoiliac occlusive disease
Classification and external resources

Plate from Gray's Anatomy showing the abdominal aorta and the iliac arteries.
ICD-9 444.0
DiseasesDB 29335
eMedicine med/2759
MeSH D007925
Leriche's syndrome (X-ray)

In medicine, aortoiliac occlusive disease, also known as Leriche's syndrome and Leriche syndrome, is atherosclerotic occlusive disease involving the abdominal aorta and/or both of the iliac arteries.



Classically, it is described in male patients as a triad of symptoms consisting of:

  1. Claudication of buttocks, thighs,
  2. Atrophy of the legs and
  3. penile impotence.

This combination is known as Leriche syndrome.[1] However, any number of symptoms may present, depending on the distribution and severity of the disease. Variable, chronic ischemia involving the lower limbs is a common presentation.[2]



The condition was first described by Robert Graham in 1814, but the condition with its triad of symptoms was ascribed to René Leriche.[3] Leriche, a French surgeon, linked the pathophysiology with the anatomy of the condition. Leriche first published on the subject based on a patient he treated with the condition at the age of 30. Following treatment the 30 year old was able to walk without pain and maintain an erection.


  1. ^ Lee BY, Guerra J (1994). "Axillofemoral bypass graft in a spinal cord injured patient with impending gangrene". The Journal of the American Paraplegia Society 17 (4): 171–6. PMID 7869060.  
  2. ^ McKinsey JF (1995). "Extra-anatomic reconstruction". Surg. Clin. North Am. 75 (4): 731–40. PMID 7638717.  
  3. ^ synd/2747 at Who Named It?

See also

External links



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