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Systematic (IUPAC) name
CAS number 189681-71-8
ATC code none
PubChem 6440763
Chemical data
Formula C18H18N2O3 
Mol. mass 310.346 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Aplindore (DAB-452) is a drug which acts as a partial agonist selective for the dopamine receptor D2.[1] It is being developed by the pharmaceutical company Neurogen as a treatment for Parkinson's disease and restless legs syndrome.[2]


  1. ^ Heinrich JN, Brennan J, Lai MH, Sullivan K, Hornby G, Popiolek M, Jiang LX, Pausch MH, Stack G, Marquis KL, Andree TH. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist. European Journal of Pharmacology. 2006 Dec 15;552(1-3):36-45. PMID 17056032
  2. ^ Neurogen licenses Aplindore from Wyeth


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