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Aprobarbital
Systematic (IUPAC) name
5-propan-2-yl- 5-prop-2-enyl- 1,3-diazinane- 2,4,6-trione
Identifiers
CAS number 77-02-1
ATC code N05CA05
PubChem 6464
ChemSpider 6221
Chemical data
Formula C 10H14N2O3  
Mol. mass 210.23 g/mol
SMILES eMolecules & PubChem
Synonyms Aprobarbital, Oramon, Allylpropymal, Alurate, 5-Isopropyl- 5-allylbarbituric acid
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
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Aprobarbital (Oramon) is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. [1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.

References

  1. ^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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