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Atipamezole: Wikis


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Systematic (IUPAC) name
CAS number 104054-27-5
ATCvet code QV03AB90
PubChem 71310
Chemical data
Formula C 14H16N2  
Mol. mass 212.290 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Veterinary use only
Routes  ?

Atipamezole (brand name Antisedan, Pfizer) is a synthetic alpha2-adrenergic antagonist, indicated for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.[1] It has also been researched in humans as a potential anti-Parkinsonian drug.[2]


  1. ^ Pfizer Animal Health ANTISEDAN Product Overview
  2. ^ Pertovaara A, Haapalinna A, Sirviö J, Virtanen R (2005). "Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist". CNS Drug Reviews 11 (3): 273–88. PMID 16389294.  

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