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B-cell lymphoma
Classification and external resources

Micrograph showing a large B cell lymphoma. Field stain.
ICD-10 C85.1
ICD-O: 9680/0, 9699/3, 9699/3
eMedicine med/1358
MeSH D016393

The B-cell lymphomas are types of lymphoma affecting B cells. Lymphomas are "blood cancers" in the lymph glands. They develop more frequently in older adults and in immunocompromised individuals (such as those with AIDS).

B-cell lymphomas include both Hodgkin's lymphomas and most non-Hodgkins lymphomas. They are often divided into indolent (slow-growing) lymphomas and aggressive lymphomas. Indolent lymphomas respond rapidly to treatment and are kept under control (in remission) with long-term survival of many years, but are not cured. Aggressive lymphomas usually require intensive treatments, but have good prospects for a permanent cure.[1]

Prognosis and treatment depends on the specific type of lymphoma as well as the stage and grade. Treatment includes radiation and chemotherapy. Early-stage indolent B-cell lymphomas can often be treated with radiation alone, with long-term non-reoccurrence. Early-stage aggressive disease is treated with chemotherapy and often radiation, with a 70-90% cure rate.[1] Late-stage indolent lymphomas are sometimes left untreated and monitored until they progress. Late-stage aggressive disease is treated with chemotherapy, with cure rates of over 70%.[1]



Micrograph showing Hodgkin lymphoma, a type of B cell lymphoma that is usually considered separate from other B cell lymphomas. Field stain.

There are fourteen kinds of lymphomas involving B cells.



Five account for nearly three out of four patients with non-Hodgkin lymphoma:[2]


The remaining nine are much less common:[2]


Additionally, some researchers separate out lymphomas that appear result from other immune system disorders, such as AIDS-related lymphoma.

Classic Hodgkin's lymphoma and nodular lymphocyte predominant Hodgkin's lymphoma are now considered forms of B-cell lymphoma.[4]

See also


  1. ^ a b c Merck Manual home edition, Non-Hodgkin Lymphomas
  2. ^ a b "The Lymphomas" (PDF). The Leukemia & Lymphoma Society. May 2006. p. 12. Retrieved 2008-04-07. 
  3. ^ Mazen Sanoufa, Mohammad Sami Walid, Talat Parveen (2010). "B-Cell Lymphoma of the Thoracic Spine Presenting with Spinal Cord Pressure Syndrome". JOCMR 2 (1): 53-54. doi:10.4021/jocmr2010.02.258w. 
  4. ^ "HMDS: Hodgkin's Lymphoma". Retrieved 2009-02-01. 

External links


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