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Bendiocarb: Wikis

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Bendiocarb
Bendiocarb.png
IUPAC name
Identifiers
CAS number 22781-23-3
PubChem 2314
ATCvet code QP53AE03
SMILES
InChI
InChI key XEGGRYVFLWGFHI-UHFFFAOYAG
ChemSpider ID 2224
Properties
Molecular formula C11H13NO4
Molar mass 223.23 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Bendiocarb is an acutely toxic carbamate insecticide used in public health and agriculture and is effective against a wide range of nuisance and disease vector insects. Many bendiocarb products are or were sold under the tradenames "Ficam" and "Turcam."

All bendiocarb-containing products in the United States were recently cancelled, after its manufacturers voluntarily chose to pull their products off the market, rather than conduct additional safety studies required by the EPA.[1] In other countries, it is still used in homes, industrial plants, and food storage sites to control mosquitoes, flies, wasps, ants, fleas, cockroaches, silverfish, and ticks but can be used against a wide variety of insects as well as snails and slugs. It is one of 12 insecticides recommended by the World Health Organization for use in malaria control.[2]

Bendiocarb is not considered to be carcinogenic, but it is acutely toxic. Like other carbamates, it reversibly inhibits acetylcholinesterase, an enzyme required for normal transmission of nerve impulses. Bendiocarb binds to the active site of this enzyme leading to an accumulation of acetylcholine, which is required for the transmission of nerve impulses, at nerve muscle sites.[1]

Bendiocarb was invented in 1971 and was first introduced into the market by Fisons Ltd. It is currently marketed by Bayer CropScience and Kuo Ching under various trade names: Ficam, Dycarb, Garvox, Turcam, Niomil, Seedox, Tattoo

Bendiocarb is highly toxic to birds and fish. In mammalian tissue, carbamates are generally excreted rapidly and do not accumulate.[1]

References

  1. ^ a b c R.E.D. Facts: Bendiocarb U.S. EPA, September 1999.
  2. ^ Sadasivaiah, Shobha; Tozan, Yesim; Breman, Joel G. (December 1, 2007), "Dichlorodiphenyltrichloroethane (DDT) for Indoor Residual Spraying in Africa: How Can It Be Used for Malaria Control?", Am. J. Trop. Med. Hyg. 77 (Suppl 6): 249–263, http://www.ajtmh.org/cgi/content/full/77/6_Suppl/249  

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