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Benzoctamine
Systematic (IUPAC) name
N-methyl-9,10-ethanoanthracene-9(10 H)-methanamine
Identifiers
CAS number 17243-09-9
ATC code N05BD01
PubChem 28425
ChemSpider 26444
Chemical data
Formula C 18H19N 
Mol. mass 249.35 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 2 to 3 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Intravenous, oral
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Benzoctamine is a drug that possesses sedative and anxiolytic properties. It is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. When co-administered with other drugs that cause respiratory depression, like morphine, it can cause increased respiratory depression. Peak effects are reached at about an hour, and effects wear off after about 2–3 hours. This drug is also used as a sedative in the hospital scene in patients who have respiratory failure.

It appears to reduce turnover of serotonin.[1]

Its effects can be variable.[2]

References

  1. ^ Lippmann W, Pugsley TA (August 1974). "Effects of benzoctamine and chlordiazepoxide on turnover and uptake of 5-hydroxytryptamine in the brain". Br. J. Pharmacol. 51 (4): 571–5. PMID 4480288.  
  2. ^ BENZOCTAMINE-A STUDY OF THE RESPIRATORY EFFECTS OF ORAL DOSES IN HUMAN VOLUNTEERS AND INTERACTIONS WITH MORPHINE IN MICE - UTTING and PLEUVRY 47 (9): 987 - British Journal of Anaesthesia







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