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Benzylbutylbarbiturate: Wikis


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Systematic (IUPAC) name
5-benzyl- 5-butyl- 1,3-diazinane- 2,4,6-trione
CAS number 66941-94-4
ATC code none
PubChem 48575
Chemical data
Formula C 15H18N2O3  
Mol. mass 274.314 g/mol
SMILES eMolecules & PubChem
Synonyms Benzylbutylbarbiturate
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Benzylbutylbarbiturate (5-benzyl- 5-(n)-butylbarbituric acid) is a rare example of a barbiturate designer drug, possibly the only such compound encountered in recent years. It was confiscated by police in Japan in 2000, and presumably was a product of clandestine manufacture as this compound has never previously been sold as a legal pharmaceutical (although it was known from the scientific literature and so was not a new chemical entity).[1] As with all designer drugs, this compound was produced in an attempt to circumvent drug laws prohibiting the use of most known barbiturate drugs, however as the drug laws in many jurisdictions (including Japan) prohibit "any 5,5-disubstituted derivative of barbituric acid", this compound was deemed to be already illegal, despite being a novel compound which had not previously been encountered.[2]


  1. ^ Alles GA, Ellis CH, Feigen GA, Redemann MA. Comparative Central Depressant Actions of some 5-Phenyl-5-Alkyl Barbituric Acids. Journal of Pharmacology and Experimental Therapeutics. 1947 Mar;89(3):356-367.
  2. ^ Ohta H, Suzuki Y, Sugita R, Suzuki S, Ogasawara K. Confiscation Case Involving a Novel Barbiturate Designer Drug. Canadian Society of Forensic Science Journal. 2000 Sep;33(3):103-110.


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