The Full Wiki

More info on Benzylpenicillin

Benzylpenicillin: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Penicillin G
Systematic (IUPAC) name
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S-(2α,5α,6β))-
CAS number 61-33-6 (free acid)
69-57-8 (sodium salt)
ATC code J01CE01 S01AA14 QJ51CE01
PubChem 5904
DrugBank DB01053
Chemical data
Formula C 16H18N2O4S 
Mol. mass 334.4 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 60 %
Metabolism hepatic
Half life 30 min
Excretion renal
Therapeutic considerations
Pregnancy cat. B(US)
Legal status Prescription only
Routes parenteral
 Yes check.svgY(what is this?)  (verify)

Benzylpenicillin, commonly known as penicillin G, is the gold standard type of penicillin. Penicillin G is typically given by a parenteral route of administration (not orally) because it is unstable in the hydrochloric acid of the stomach. Because the drug is given parenterally, higher tissue concentrations of penicillin G can be achieved than is possible with phenoxymethylpenicillin. These higher concentrations translate to increased antibacterial activity.

Specific indications for benzylpenicillin include:[1]


  1. ^ Rossi S, editor, ed (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3.  


Got something to say? Make a comment.
Your name
Your email address