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β-hexachlorocyclohexane
Beta-hexachlorocyclohexane.svg
IUPAC name
Other names β-HCH
β-Benzenehexachloride
β-BHC
Identifiers
CAS number 319-85-7 Yes check.svgY
SMILES
InChI
InChI key JLYXXMFPNIAWKQ-CDRYSYESBR
ChemSpider ID 10468512
Properties
Molecular formula C6H6Cl6
Molar mass 290.83 g/mol
 Yes check.svgY (what is this?)  (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

β-hexachlorocyclohexane (β-HCH) is an organochloride which is one of the isomers of hexachlorocyclohexane (HCH).[1] It is a byproduct of the production of the insecticide lindane (γ-HCH). It is typically constitutes 5-14% of technical grade lindane,[2] though it has not been produced or used in the United States for more than 20 years.[1]

This pesticide was widely used during the 1960s and 1970s, particularly on cotton plants. Although banned as a pesticide more than 30 years ago, traces of beta-HCH can still be found in water and soil. Animal studies show that organochlorine pesticides, including beta-HCH, are neurotoxic, cause oxidative stress, and damage the brain's dopaminergic system. Human studies show that exposure to beta-HCH is linked to Parkinson's and Alzheimer's disease [3]. Beta-HCH was present in elevated levels in some patients as recently as 2009.

See also

References

  1. ^ a b Toxicological Profile for Alpha-, Beta-, Gamma-, and Delta-Hexachlorocyclohexane, U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, August 2005
  2. ^ beta-hexachlorocyclohexane (Beta HCH), Draft Risk Profile, May 2007
  3. ^ Medscape Medical News, Pesticide Exposure Linked to Parkinson's, Alzheimer's Disease, July 2009

External links

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