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Bifonazole: Wikis

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1 : 1 mixture (racemate)
Systematic (IUPAC) name
(RS)-1-[phenyl(4-phenylphenyl)methyl]-1H-imidazole
Identifiers
CAS number 60628-96-8
ATC code D01AC10
PubChem 2378
DrugBank DB04794
ChemSpider 2287
Chemical data
Formula C22H18N2 
Mol. mass 310.392 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status OTC (US)
Routes topic
 Yes check.svgY(what is this?)  (verify)

Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark CANESPOR in ointment form.

Mechanism of action of bifonazole

Bifonazole has dual mode of action - it blocks transformation of 24-methylendihydrolanosterole to desmethylsterol in fungi together with inhibition of HMG-CoA. That's why it has fungicidal properties against dermatophytes. This makes the difference among other antifungal drugs.

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