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Bispecific monoclonal antibody: Wikis


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A bispecific monoclonal antibody is a monoclonal antibody that binds to two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory.

One benefit of this approach is that it is possible for such an antibody to simultaneously bind to a cytotoxic cell (using a receptor like CD3) and a target cell (like CD19.)[1]

Types of bispecific monoclonal antibodies include trifunctional antibodies and bi-specific T-cell engagers.


  1. ^ EuroBATH Consortium Home-Page

External links

PD-icon.svg This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".


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