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Brallobarbital: Wikis


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Systematic (IUPAC) name
5-(2-bromoprop-2-en-1-yl)- 5-(prop-2-en-1-yl) pyrimidine- 2,4,6(1H,3H,5H)- trione
CAS number 561-86-4
ATC code none
PubChem 68416
ChemSpider 61699
Chemical data
Formula C 10H11BrN2O3  
Mol. mass 287.110 g/mol
SMILES eMolecules & PubChem
Synonyms Brallobarbital
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
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Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Brallobarbital is a barbiturate derivative invented in 1964. It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine.[1] The long half-life of this combination of drugs tended to cause a hangover effect the next day,[2] and Vesparax fell into disuse once newer drugs with less side effects had been developed.[3]


  1. ^ Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)
  2. ^ Yih TD, Rossum JM. Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication. Xenobiotica. 1976 Jun;6(6):355-62.
  3. ^ Fischbach R. Efficacy and safety of midazolam and vesparax in treatment of sleep disorders. British Journal of Clinical Pharmacology. 1983;16 Suppl 1:167S-171S.


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