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Captodiame
Systematic (IUPAC) name
2-[(4-butylsulfanylphenyl)-phenyl-methyl]
sulfanyl-N,N-dimethylethanamine
Identifiers
CAS number 486-17-9
ATC code N05BB02
PubChem 10240
Chemical data
Formula C 21H29NS2  
Mol. mass 359.594 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral

Captodiame (INN, also known as captodiamine) is an anxiolytic. It is a derivative of diphenhydramine.[1]

A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.[1]

References

  1. ^ a b Mercier-Guyon C, Chabannes JP, Saviuc P (2004). "The role of captodiamine in the withdrawal from long-term benzodiazepine treatment". Curr Med Res Opin 20 (9): 1347–55. doi:10.1185/030079904125004457. PMID 15383182.   Free full text with registration
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