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Cathine
Systematic (IUPAC) name
(1S,2S)-2-amino-1-phenylpropan-1-ol
Identifiers
CAS number 492-39-7
ATC code A08AA07
PubChem 441457
Chemical data
Formula C 9H13NO 
Mol. mass 151.206
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule IV (US)
Routes Oral

Cathine, also known as d-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and likely contributes to its overall effects.

Contents

Pharmacology

Like other amphetamines such as cathinone and ephedrine, cathine acts as a releasing agent of norepinephrine and epinephrine, or as a norepinephrine releasing agent (NRA). It also acts as a dopamine releasing agent (DRA) to a lesser extent.

Chemistry

Cathine is one of the optical isomers of phenylpropanolamine (PPA).

Regulation

The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bars cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances.[1] In the United States, it is classified as a Schedule IV controlled substance.

Cathine is found in shrub Catha edulis.

In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. It can only be used legally by health professionals and for university research purposes. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000 (HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 (HKD) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a HK$ 1,000,000 fine and/or 7 years of jail time.

See also

References








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