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Cefpiramide: Wikis

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Cefpiramide
Systematic (IUPAC) name
(6R)-7-{[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-
4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino}-
3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number 70797-11-4
ATC code J01DD11
PubChem 107654
DrugBank APRD00856
Chemical data
Formula C 25H24N8O7S2  
Mol. mass 612.64 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 93% to 99.3%
Metabolism  ?
Half life 4.44 hours
Excretion Renal and fecal
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Intravenous, intramuscular

Cefpiramide is a third-generation cephalosporin antibiotic.

External links

  • Wang H, Yu Y, Xie X, Wang C, Zhang Y, Yuan Y, Zhang X, Liu J, Wang P, Chen M (2000). "In-vitro antibacterial activities of cefpiramide and other broad-spectrum antibiotics against 440 clinical isolates in China.". J Infect Chemother 6 (2): 81–5. doi:10.1007/PL00012156. PMID 11810540.  
  • Iakovlev V, Vishnevskiĭ V, Khlebnikov E, Khadin I, Plavlova M, Elagina L, Izotova G (1995). "[Cefpiramide (Tamicin) in the treatment of purulent complications of abdominal surgery]". Antibiot Khimioter 40 (9): 30–4. PMID 8651827.  
  • Sampi K, Hattori M (1992). "[Comparative study of cefpiramide + amikacin versus piperacillin + amikacin in granulocytopenic patients: a randomized, prospective study]". Gan To Kagaku Ryoho 19 (9): 1315–20. PMID 1503486.  
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