The Full Wiki

Cevimeline: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
2-methyspiro (1,3- oxathiolane- 5,3) quinuclidine
CAS number 107233-08-9
ATC code N07AX03
PubChem 83898
DrugBank APRD00224
ChemSpider 75707
Chemical data
Formula C 10H17NOS 
Mol. mass 489.565 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Protein binding < 20%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. C
Legal status Rx only
Routes Oral
 Yes check.svgY(what is this?)  (verify)

Cevimeline is a parasympathomimetic and muscarinic agonist,[1] with particular effect on M3 receptors. It is used in the treatment of dry mouth associated with Sjögren's syndrome.


Mechanism of action

By activating the M3 receptors of the parasympathetic nervous system, cevimeline stimulates secretion by the salivary glands, thereby alleviating dry mouth.

Side effects

Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. [2]


External links



Got something to say? Make a comment.
Your name
Your email address