The Full Wiki

More info on Chlormezanone

Chlormezanone: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
CAS number 80-77-3
ATC code M03BB02
PubChem 2717
DrugBank APRD00865
ChemSpider 2616
Chemical data
Formula C 11H12ClNO3S 
Mol. mass 273.737 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 40.5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status  ? (US)
Routes Oral
 Yes check.svgY(what is this?)  (verify)

Chlormezanone (marketed under the brandname Trancopal) is a drug used as an anxiolytic and a muscle relaxant.

Its use was discontinued in many countries in 1996, due to rare but serious cases of toxic epidermal necrolysis.


  • Wollina U, Hipler U, Seeling A, Oelschlager H (2005). "Investigations of interactions of chlormezanone racemate and its enantiomers on human keratinocytes and human leucoytes in vitro.". Skin Pharmacol Physiol 18 (3): 132–8. doi:10.1159/000084910. PMID 15897685.  
  • Seeling A, Oelschläger H, Rothley D (2000). "Important pharmaceutical-chemical characteristics of the central muscle relaxant chlormezanone". Pharmazie 55 (4): 293–6. PMID 10798243.  
  • Oelschläger H, Klinger W, Rothley D, Seeling A, Bockhard H, Hofmann B, Machts H, Riederer H, Rackur H (1998). "[Cleavage and biotransformation of the central muscle relaxant chlormezanone]". Pharmazie 53 (9): 620–4. PMID 9770210.  
  • Gautier V, Vincon G, Demotes-Mainard F, Albin H (1990). "[Pharmacokinetics of chlormezanone in healthy volunteers] (original in French)". Pharmazie 45 (4): 315–9. PMID 2399514.  


Got something to say? Make a comment.
Your name
Your email address