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Chloroxylenol
Systematic (IUPAC) name
4-chloro-3,5-dimethylphenol
Identifiers
CAS number 88-04-0
ATC code D08AE05
PubChem 2723
ChemSpider 21106017
Chemical data
Formula C 8H9ClO 
Mol. mass 156.609
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Chloroxylenol (4-chloro-3,5-dimethylphenol) is a chemical compound with the formula C8H9ClO and CAS number 88-04-0. It is commonly used in antibacterial soaps such as Dettol; studies have shown a low anti microbial activity which is enhanced by additives. Its antibacterial action is due to disruption of cell membrane potentials.[1]

Chloroxylenol is not significantly toxic to humans and other mammals but is toxic to fish. It is a mild skin irritant and may trigger allergic reactions in some individuals. Cross sensitivity with chlorocresol is common.[2]

References

  1. ^ Aly, R; Malbach, H (1988). "Comparative antibacterial efficacy of a 2-minute surgical scrub with chlorhexidine gluconate, povidone-iodine, and chloroxylenol sponge-brushes". American Journal of Infection Control 16: 173. doi:10.1016/0196-6553(88)90029-6.  
  2. ^ Ascenzi, Joseph M. (1996). "Chloroxylenol: an old-new antimicrobial". Handbook of disinfectants and antiseptics. New York: M. Dekker. ISBN 9780824795245. http://books.google.de/books?hl=de&lr=&id=tFPW4D70BmgC&oi=fnd&pg=PA265.  

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