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Chlorphenesin: Wikis

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Chlorphenesin
Systematic (IUPAC) name
(3-(4-chlorophenoxy)-2-hydroxypropyl)carbamate
Identifiers
CAS number 886-74-8
ATC code D01AE07
PubChem 2724
Chemical data
Formula C 10H12ClNO4  
Mol. mass 245.660 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 86–92 °C (187–198 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion urine
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Chlorphenesin (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms.[1][2]

It also has antifungal and some antibacterial properties and is thus classified as an antifungal for topical use by the WHO.[3]

Physical Properties

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Melting Point

86-92 deg. Celsius[4]

References

  1. ^ Okuyama S, Aihara H. Antinociceptive effect of chlorphenesin carbamate in adjuvant arthritic rats. Research Communications in Chemical Pathology and Pharmacology. 1987 Feb;55(2):147-60. PMID 3823606
  2. ^ Kurachi M, Aihara H. Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats. Japanese Journal of Pharmacology. 1984 Sep;36(1):7-13. PMID 6503049
  3. ^ ATC code D01AE07
  4. ^ Salim, E.F.; Booth, R.E. (1967). "Qualitative and quantitative tests for chlorphenesin carbamate". Journal of Pharmaceutical Sciences 56 (5). http://www3.interscience.wiley.com/journal/113292953/abstract. Retrieved 2009-06-23.  

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