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Systematic (IUPAC) name
5-[3-(dimethylamino)propyl]-10,11-dihydro-5 H-dibenzo[b,f]azepine-3-carbonitrile
CAS number 66834-24-0
ATC code none
PubChem 48126
Chemical data
Formula C 20H23N3  
Mol. mass 305.417 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Cianopramine (Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine which acts as a serotonin reuptake inhibitor[1] and weak serotonin receptor antagonist.[2]

See also


  1. ^ Kenny M, Lenehan TJ, Lambe R, Darragh A, Brick I, Omer LM. Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers. Psychopharmacology (Berlin). 1983;79(4):304-7. PMID 6407042
  2. ^ Pawłowski L, Kwiatek H, Górka Z. Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors? Journal of Neural Transmission. 1981;52(1-2):61-72. PMID 7288439

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