The Full Wiki

More info on Ciclotizolam

Ciclotizolam: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Ciclotizolam
Systematic (IUPAC) name
2-Bromo-4-(o-chlorophenyl)-9-cyclohexyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine
Identifiers
CAS number 58765-21-2
ATC code none
PubChem 71949
Chemical data
Formula C 20H18BrClN4S 
Mol. mass 461.806
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Ciclotizolam (WE-973) is a drug which is a thienobenzodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABAA receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.[1][2]

See also

References

  1. ^ Weber KH, Kuhn FJ, Böke-Kuhn K, Lehr E, Danneberg PB, Hommer D, Paul SM, Skolnick P (February 1985). "Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines')". European Journal of Pharmacology 109 (1): 19–31. PMID 2986988.  
  2. ^ Ikeda M, Weber KH, Bechtel WD, Malatynska E, Yamamura HI (1989). "Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles". Life Sciences 45 (4): 349–58. PMID 2569655.  
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message