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Cinitapride: Wikis

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Systematic (IUPAC) name
CAS number 66564-14-5
ATC code none
PubChem 68867
ChemSpider 62099
Chemical data
Formula C21H30N4O4 
Mol. mass 402.49 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral

Cinitapride (Cidine, Blaston, Pemix) is a gastroprokinetic agent and antiulcer agent of the benzamide class which is marketed in Spain and Mexico.[1][2] It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.[3][4]

See also


  1. ^ Robert M, Salvà M, Segarra R, et al. (July 2007). "The prokinetic cinitapride has no clinically relevant pharmacokinetic interaction and effect on QT during coadministration with ketoconazole". Drug Metabolism and Disposition: the Biological Fate of Chemicals 35 (7): 1149–56. doi:10.1124/dmd.106.010835. PMID 17437965. 
  2. ^ Fernández AG, Massingham R (January 1985). "Peripheral receptor populations involved in the regulation of gastrointestinal motility and the pharmacological actions of metoclopramide-like drugs". Life Sciences 36 (1): 1–14. PMID 2981378. 
  3. ^ Alarcón-de-la-Lastra Romero C, López A, Martín MJ, la Casa C, Motilva V (April 1997). "Cinitapride protects against ethanol-induced gastric mucosal injury in rats: role of 5-hydroxytryptamine, prostaglandins and sulfhydryl compounds". Pharmacology 54 (4): 193–202. PMID 9211565. 
  4. ^ Alarcón de la Lastra C, La Casa C, Martin MJ, Motilva V (March 1998). "Effects of cinitapride on gastric ulceration and secretion in rats". Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.] 47 (3): 131–6. PMID 9562338. 

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