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Clobetasone
Systematic (IUPAC) name
(1R,2S,10S,11S,13 S,14R,15S)-14-(2-chloroacetyl)-1-fluoro-14-hydroxy-2,13,15-trimethyltetracyclo[8.7.0.0 2,7.011,15]heptadeca-3,6-diene-5,17-dione
Identifiers
CAS number 54063-32-0
ATC code D07AB01 S01BA09
PubChem 71387
Chemical data
Formula C 22H26ClFO4  
Mol. mass 408.891
Synonyms (8S,9R,10S,13S,14S,16 S,17R)-17-(2-Chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6 H-cyclopenta[a]phenanthrene-3,11-dione
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes topical

Clobetasone (INN[1]) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema and other forms of dermatitis, and ophthalmology.

It is available as clobetasone butyrate under the brand name Eumovate[2] or Trimovate,[3] both manufactured by GlaxoSmithKline.

References

  1. ^ United Nations Statistics Division - Classifications Registry - Alphabetical index for HS 2002 Entries starting with 'C' (page 310 of 422)
  2. ^ Eumovate cream/ointment, NetDoctor.co.uk
  3. ^ Trimovate cream, NetDoctor.co.uk
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